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Portrait of Daniel C F Costache

Research interests

  • Traumatic brain injury (TBI)
  • Multiscale and multiphysics modelling
  • Continuum damage mechanics
  • Finite element modelling

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PhD student

Daniel C F Costache

PhD Student

Daniel is a PhD student working on traumatic brain injury (TBI). He is working on developing more biofidelic multiscale, multiphysics models of TBI, aiming to directly link mechanical loading of the brain to the symptoms that follow, such as loss of consciousness. His work aims to apply continuum damage mechanics to the brain to understand how injury disrupts neural circuits, and to bring that understanding into FEM based models.

He began his PhD in September 2026 in the first cohort of Imperial’s School of Convergence Science, under the joint supervision of Prof Mazdak Ghajari at HEAD Lab and Prof David Sharp from the Department of Brain Sciences.

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